Portfolio
Companies We Back
Investments across Theodorus IV and Fund V, including historical investments made under earlier mandates.

Theodorus IV
17 companiesApaxen
Biotechnology research targeting chronic inflammation, with a primary focus on developing new approaches to pulmonary arterial hypertension.
Theodorus IVCascador Health / moveUP
Combines patient programs, clinical software and healthcare data to generate real-world evidence across the development and use of therapies.
Classcraft
Educational technology built around playful, collaborative learning experiences, designed to support student motivation and engagement in the classroom.
Theodorus IVKainova Therapeutics
Develops medicines targeting G protein-coupled receptors, with research and clinical programs focused on cancer immunotherapy and inflammatory diseases.

DrugBank
Connects information on drugs, targets, diseases and clinical trials to support pharmaceutical research, clinical software and drug-development decisions.
Theodorus IVWebsite of DrugBank (opens in a new tab)Flare
Monitors online threats, including data leaks and dark-web activity, to help organizations identify and prioritize cybersecurity risks.
Theodorus IVWebsite of Flare (opens in a new tab)Gepeceron
Biotechnology research focused on small molecules targeting G protein-coupled receptors, with potential applications in solid cancers and inflammatory diseases.
Theodorus IV
Giiant Pharma
Develops localized therapies for gastrointestinal diseases, including ulcerative colitis, with an approach intended to limit exposure elsewhere in the body.
Theodorus IVHypnoVR
Combines medical hypnosis with virtual reality in digital therapies designed to support pain, stress and anxiety management in healthcare settings.
Theodorus IVWebsite of HypnoVR (opens in a new tab)
Icentia
Develops wearable cardiac-monitoring devices and provides ECG analysis services to support clinicians assessing heart rhythm over extended periods.
Theodorus IVWebsite of Icentia (opens in a new tab)
InhaTarget Therapeutics
Develops targeted inhaled medicines for severe respiratory diseases, with an initial focus on treatment approaches for lung cancer.

Kaspard
Provides contactless fall-detection and activity-monitoring technology to help care teams understand incidents and support residents in hospitals and care homes.
Theodorus IVWebsite of Kaspard (opens in a new tab)Moonshot Health
Digital health company focused on using digital biomarkers to support preventive, continuous and collaborative care beyond episodic medical appointments.
Theodorus IVNeuvasq Biotechnologies
Develops antibody therapies designed to restore blood-retina and blood-brain barriers for vascular eye diseases and neurological disorders.

Simmunome
Combines biological modelling and machine learning to simulate disease mechanisms, evaluate drug targets and identify biomarkers for drug-development decisions.
Theodorus IVWebsite of Simmunome (opens in a new tab)
Ability Biotherapeutics
Uses artificial intelligence and antibody engineering to develop selective therapeutics targeting immune cells involved in autoimmune and inflammatory diseases.
Theodorus IVNeomabs Biotechnologies
Develops therapeutic antibodies targeting cancer-associated neoantigens, building on research aimed at new immunotherapies for difficult-to-treat pediatric leukemias.
Theodorus IV
Fund V
04 companies
Innospera Pharma
Develops small-molecule medicines targeting PPAR signalling, with programs focused on fibrosis, cardiometabolic conditions and other chronic diseases.
Fund VReverb Therapeutics
Develops antibody medicines that redirect the body’s own cytokine signals, with programs addressing cancer and other immune-related conditions.
Leaflet Solutions
Develops a catheter designed to modify the mitral valve’s anterior leaflet and help expand eligibility for transcatheter mitral valve replacement.
Fund VAntegrade Medical
Develops devices for antegrade transseptal access in structural heart procedures, with an approach intended to support treatment of high-risk cardiac conditions.
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